DESCRIPTION:
Amicin 25 is a clear solution of amikacin Sulfate for injection use only.
ACTIONS:
Amikacin, like other aminoglycoside antibiotics, is a bactericidal agent that exerts its action at the level of the bacterial ribosome. Amikacin has been shown to be effective against many aminoglycoside-resistant strains due to its ability to resist degradation by aminoglycoside inactivating enzymes known to affect gentamicin, tobramycin and kanamycin.
Microbiology
Amikacin has been shown to be effective in the treatment of skin and soft tissue infections caused by Pseudomonas sp and Escherichia coli and in urinary tract infections caused by Escherichia coli and Proteus sp.
DOSAGE & ADMINISTRATION:
Amikacin Sulfate Injection should be administered subcutaneously or intramuscularly at a dosage of 10 mg/kg (5 mg/lb) twice daily. Dogs with skin and soft tissue infections should be treated for a minimum of 7 days and those with genitourinary infections should be treated for 7 to 21 days or until culture negative and asymptomatic. If no response is observed after three days of treatment, therapy should be discontinued and the case re-evaluated. Maximum duration of therapy should not exceed 30 days.
